Latest Articles

Latest Articles have been peer-reviewed and accepted, which are not yet assigned to volumes/issues, but are citable by Digital Object Identifier (DOI).
CCA, a cassane diterpene from Caesalpinia bonduc ameliorates cognition impairment in Alzheimer’s disease mice by regulating neuroinflammation and autophagy
Zhou Jiayu, Zhang Wei, Yang Yiren, Jin Yue, Li Xiaoyu, Wang Yuxin, Lu Hongyuan, Gao Huiyuan, Jiang Xiaowen
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Icariin against neuroinflammation: emerging evidence for gut-brain axis modulation involving short-chain fatty acids, vagal signaling, and extracellular vesicles
Wu Changzheng, Guo Lijiao, Sun Xiaoyu, Zhu Jinpu, Zhao Zhehao, Qi Shuo, Li Yaru, Li Hongyang, Zhao Renshuang, Xiu Zhiru, Zhu Guangze, Li Yiquan
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Brevilin A induces mitochondrial dysfunction and endoplasmic reticulum stress in breast cancer through WWP2-mediated KLF5 degradation
Si Yuan, Peng Wenkang, Liu Ling, Tan Miao, Wang Sicheng, Zheng Chengling, Peng Peng, Xia Qiang, Zheng Kainan, Liu Xuewen, Liu Ying, Tan Yan
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Artemisinin derived from Artemisia annua L. promotes thrombopoiesis via targeting FLT3: a novel strategy for thrombocytopenia management
Mei Xinyue, Liu Sheng, Zhou Linglin, Wang Yiling, Hu Tianci, Qi Xiao, Li Fengyu, Huang Feihong, Peng Wenchuan, Shen Xinyue, Huang Siyu, Lei Mengying, Wu Anguo, Wu Jianming, Luo Jiesi, Wang Long
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Quercetin activates lysosomal function to ameliorate neuroinflammation and cognitive deficits in chronic cerebral hypoperfusion
Chen Yao, Jiang Yibin, Song Tang, Chen Yongxin, Li Jing, Zhi Ning, Wei Hongqiao, Huang Kaiyong, Huang Xiaowei, Lu Guodong, Zhou Jing
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Exosomes, a potential approach to enhance the therapeutic effects of traditional Chinese medicine
Huang Tengteng, Wang Ziyu, Zhao Yu, Fang Weirong
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Isoimperatorin regulates hepatic fibrosis through LXRα/β-HMGB1/NLRP3 axis: insights into the apoptosis of activated hepatic stellate cells in hepatic microenvironment
Liu Saihu, Xuan Meiyan, Gao Chong, Wang Chenyu, Lian Lihua, Nan Jixing, Cui Zhenyu, Wu Yanling
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Sesquiterpene lactones from the traditional Chinese medicine Eupatorium lindleyanum DC. and their preliminary protective effects against nano-SiO2-induced injury
Xu Qing, Qing Mengli, Wang Chenhui, Dang Wen, Bai Xiaolin, Chen Gang, Zhou Di, Li Ning
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Neferine sensitizes oral squamous cell carcinoma to cisplatin by disrupting the CCDC43-PNKP interaction
Lin Yangfeng, Zheng Xiongzhou, Tang Yue, Chen Jianguang, Chen Xiao, Liang Zixi, Lin Xian, Zhu Xiaofeng
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Mechanisms and translational targets of coronary microvascular endothelial injury in ischemic cardiomyopathy: from hypoxic stress to microenvironmental remodeling
Wang Tianen, Li Zhaoling, Shen Xiaoxuan, Chang Zhen, Luo Yalin, Sun Zijin, Zhang Zuhe, Chang, Tong Ying
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Self-Assembled Nanosystems Incorporating Traditional Chinese Medicine: Design, Function, and Therapeutic Performance
Qin Yi, Fan Yuanhe, Ye Heng, Wu Haoyuan, Zhang Qing, Zheng Caixia, Zhou Xunyong, Zhao Longshan, Guan Xuefeng
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Natural product screening strategies targeting the Nrf2 pathway: Current status, challenges, and future perspectives
Liu Haiyi, Su Erzheng, Duan Jin-ao, Xiao Ping
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Abnormal Mitochondrial Function in Cardiac Hypertrophy: From Mechanisms to Perspectives on Treatment with Traditional Chinese Medicine
Zhang Errui, Shi Junkai, Liu Guangyao, Zhu Yulong, VanDusen Nathan J., Tao Houchao, Gu Weiliang
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Natural Products Modulating Immune Checkpoints: From Medicinal Chemistry Insights to Translational Advances in Overcoming Tumor Immunotherapy Bottlenecks
Yuan Ting, Zhao Yichao, Ruan Bingxin, Chang Zhenhui, Jiang Feng
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Sasang Constitutional Phenotyping and the Evidence Gap in Precision Herbal Therapeutics: A Multi-Omics Roadmap
Amin Adnan
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Spatholobus suberectus Dunn Attenuates Hepatic Fibrogenesis by Disrupting the MFAP4 Mediated TGF-β1/LOXL1 Positive Feedback Loop
He Qingman, Yao Huan, Sui Yue, Gao Yongxiang, Chen Jianping
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Ecology-Guided and Technology-Enabled Strategies in the Discovery of Marine Natural Products for Drug Development
Feng Ran-Qi, Armel Kouame Kra Wilfried, Hao Yi, Osman Ezzat E. A., Guo Yue-Wei, Li Xu-Wen
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Quercetin reverses the breast cancer-promoting effects of depression by targeting PPARγ
Wu Yingchao, Liang Yuqi, Chen Liushan, Chen Jieting, Huang Junfeng, Yang Congwen, Zuo Qian, Chen Qianjun
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Multi-omics profiling elucidates the optimal cultivation time and chemical markers for animal-derived medicine Bungarus Parvus
Yu Kaiquan, Qiao Yajun, Wang Cuicui, Xu Meng, Wei Wenlong, Zhang Yesong, Li Tingwei, Bi Qirui, Zhang Jianqing, Guo Dean
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Levistilide A restrains myocardial fibrosis by targeting malate dehydrogenase 2
Pan Ting, Cheng Yingying, Yan Yutian, Cao Wenjia, Jiang Qingjia, Li Ping, Zeng Hao
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Angeloylgomisin O from YiQiFuMai lyophilized injection attenuates heart failure by inhibiting endothelial-mesenchymal transition via ACE2
Dai Sufang, Huang Zixuan, Liu Jincheng, Wu Lingling, Zhao Qingfei, Gong Shuaishuai, Zhang Yuanyuan, Yu Boyang, Li Fang, Kou Junping
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Natural cyclopeptide RA-V induces ER stress and promotes HRD1-mediated c-Myc degradation to inhibit pancreatic cancer stemness
Jiang Zhuangzhuang, Wu Yingwei, Cao Feng, Wang Jianghao, Ye Shuqing, Sui Yihang, Tan Ninghua
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Organ-on-a-Chip in Natural Product Research: Advancing Translational ADME, Efficacy and Safety Assessment
Hao Lijun, Ge Ye, Wang Tingting, Wang Guangji, Zhang Jingwei
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Hydrolyzed Ginsenosides of Panax notoginseng Flowers Attenuate Alcoholic Liver Disease by Inhibiting Oxidative Stress and Lipid Accumulation
Shen Hong, Ma Li-Juan, Wang Kang-Hui, Zhou Jun-Yi, Liu Jia-Yue, Wan Jian-Bo
DOI: 10.1016/S1875-5364(26)61118-1
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Traditional Chinese medicine-based drug delivery systems for anti-tumor therapies
Yang Lin, Wang Yani, Ye Xietao, Liu Qiaoming, Qu Ding, Chen Yan
DOI: 10.1016/S1875-5364(25)60860-0
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Research progress of small-molecule natural medicines for the treatment of ischemic stroke
Liu Kui, Wang Ling, Pang Tao
DOI: 10.1016/S1875-5364(24)60712-0
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