Latest Articles

Latest Articles have been peer-reviewed and accepted, which are not yet assigned to volumes/issues, but are citable by Digital Object Identifier (DOI).
Neferine sensitizes oral squamous cell carcinoma to cisplatin by disrupting the CCDC43-PNKP interaction
Lin Yangfeng, Zheng Xiongzhou, Tang Yue, Chen Jianguang, Chen Xiao, Liang Zixi, Lin Xian, Zhu Xiaofeng
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Quercetin reverses the breast cancer-promoting effects of depression by targeting PPARγ
Wu Yingchao, Liang Yuqi, Chen Liushan, Chen Jieting, Huang Junfeng, Yang Congwen, Zuo Qian, Chen Qianjun
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Artemisinin derived from Artemisia annua L. promotes thrombopoiesis via targeting FLT3: a novel strategy for thrombocytopenia management
Mei Xinyue, Liu Sheng, Zhou Linglin, Wang Yiling, Hu Tianci, Qi Xiao, Li Fengyu, Huang Feihong, Peng Wenchuan, Shen Xinyue, Huang Siyu, Lei Mengying, Wu Anguo, Wu Jianming, Luo Jiesi, Wang Long
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Single-cell analysis reveals synergistic therapeutic mechanisms of Shenqi Fuzheng formula against acute myocardial infarction
Wang Menglei, Li Xiang, Gao Meng, Zhu Bingjie, Wei Tiezhu, Huang Wenhua, Fan Xiaohui, Liao Jie
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Data mining and multi-omics profiling to reveal the mechanisms of cold/hot property of traditional Chinese medicine in Alzheimer’s disease treatment
Zhu Mingtao, Wang Yu, Tang Haipeng, Sun Yanping, Feng XiaoTao, Wang Qiuhong, Kuang Haixue
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From bench to beside: luteolin’s therapeutic promise in neurological disorders
Zhu Wenjun, Yuan Naijun, Tang Manshi, She Kaijie, Chen Man, Huang Minyi, Feng Ruotong, Ma Qingyu, Chen Jiaxu
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Hyperperins A–X, fusicoccane diterpenoids including an unreported 5/7/5/3 tetracyclic carbon skeleton from Hypoestes purpurea and their T-type calcium channel inhibitory activity
Ding Linfen, Hu Ming, Wei Qiaoling, Yin Shihuan, Wang Xinying, Sai Lu, Li Wenyan, Wu Xingde
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Broad-spectrum anticoronaviral activity of the traditional herbal medicine Mahuangtang by targeting the multistep viral infection process: virus entry, Mpro, PLpro, RdRp and IFN induction
Yoon Jiwon, Jin Young-Hee, Kim Yeonhwa, Oh Eun Young, Park Sohyun, Min Jung Sun, Ha In Jin, Kim Sanghyun, Kim Hakjin, Lee Sang-Myeong, Kwon Sunoh
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Targeting senescence-associated fibrotic signatures identifies syringin as an effective modulator of the ATR/CHK1–p53 axis in idiopathic pulmonary fibrosis
Wang Yuyang, Yin Guanghui, Niu Mixing, Wang Wei, Liao Zhenyun, Yang Lei, Wu Chunli, Cao Yu, Gao Kai, Dong Zhaoxing
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Kaurepenoid A, a 2-nor-ent-kaurane diterpenoid with P-glycoprotein-mediated reversal of multidrug resistance activity from the fungus Bipolaris sp.
Shen Yong, Ding Nanjin, Zheng Meijia, Guo Tianyuan, Gu Xiaoxia, Liang Yu, Chen Chunmei, Li Qin, Zhang Yonghui, Zhu Hucheng
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Icariin enhances PINK1-associated mitophagy to attenuate NLRP3/GSDMD-related microglial pyroptosis and cognitive impairment in Alzheimer’s disease
Fan Longmin, Jiang Haitao, Yi Min, Peng Weijun, Zhang Zheyu
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Isoimperatorin regulates hepatic fibrosis through LXRα/β-HMGB1/NLRP3 axis: Insights into the apoptosis of activated hepatic stellate cells in hepatic microenvironment
Liu Saihu, Xuan Meiyan, Gao Chong, Wang Chenyu, Lian Lihua, Nan Jixing, Cui Zhenyu, Wu Yanling
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CCA, a cassane diterpene from Caesalpinia bonduc ameliorates cognition impairment in Alzheimer’s disease mice by regulating Neuroinflammation and Autophagy
Zhou Jiayu, Zhang Wei, Yang Yiren, Jin Yue, Li Xiaoyu, Wang Yuxin, Lu Hongyuan, Gao Huiyuan, Jiang Xiaowen
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Icariin against neuroinflammation: emerging evidence for gut-brain axis modulation involving short-chain fatty acids, vagal signaling, and extracellular vesicles
Wu Changzheng, Guo Lijiao, Sun Xiaoyu, Zhu Jinpu, Zhao Zhehao, Qi Shuo, Li Yaru, Li Hongyang, Zhao Renshuang, Xiu Zhiru, Zhu Guangze, Li Yiquan
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Brevilin A induces mitochondrial dysfunction and endoplasmic reticulum stress in breast cancer through WWP2-mediated KLF5 degradation
Si Yuan, Peng Wenkang, Liu Ling, Tan Miao, Wang Sicheng, Zheng Chengling, Peng Peng, Xia Qiang, Zheng Kainan, Liu Xuewen, Liu Ying, Tan Yan
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Exosomes, a Potential Approach to Enhance the Therapeutic Effects of Traditional Chinese Medicine
Huang Tengteng, Wang Ziyu, Zhao Yu, Fang Weirong
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Quercetin Activates Lysosomal Function to Ameliorate Neuroinflammation and Cognitive Deficits in Chronic Cerebral Hypoperfusion
Chen Yao, Jiang Yi-Bin, Song Tang, Chen Yong-Xin, Li Jing, zhi Ning, Wei Hong-Qiao, Huang Kai-Yong, Huang Xiao-Wei, Lu Guo-Dong, Zhou Jing
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Levistilide A restrains myocardial fibrosis by targeting malate dehydrogenase 2
Pan Ting, Cheng Yingying, Yan Yutian, Cao Wenjia, Jiang Qingjia, Li Ping, Zeng Hao
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Angeloylgomisin O from YiQiFuMai lyophilized injection attenuates heart failure by inhibiting endothelial-mesenchymal transition via ACE2
Dai Sufang, Huang Zixuan, Liu Jincheng, Wu Lingling, Zhao Qingfei, Gong Shuaishuai, Zhang Yuanyuan, Yu Boyang, Li Fang, Kou Junping
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Natural cyclopeptide RA-V induces ER stress and promotes HRD1-mediated c-Myc degradation to inhibit pancreatic cancer stemness
Jiang Zhuangzhuang, Wu Yingwei, Cao Feng, Wang Jianghao, Ye Shuqing, Sui Yihang, Tan Ninghua
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Organ-on-a-Chip in Natural Product Research: Advancing Translational ADME, Efficacy and Safety Assessment
Hao Lijun, Ge Ye, Wang Tingting, Wang Guangji, Zhang Jingwei
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Hydrolyzed Ginsenosides of Panax notoginseng Flowers Attenuate Alcoholic Liver Disease by Inhibiting Oxidative Stress and Lipid Accumulation
Shen Hong, Ma Li-Juan, Wang Kang-Hui, Zhou Jun-Yi, Liu Jia-Yue, Wan Jian-Bo
DOI: 10.1016/S1875-5364(26)61118-1
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Traditional Chinese medicine-based drug delivery systems for anti-tumor therapies
Yang Lin, Wang Yani, Ye Xietao, Liu Qiaoming, Qu Ding, Chen Yan
DOI: 10.1016/S1875-5364(25)60860-0
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Research progress of small-molecule natural medicines for the treatment of ischemic stroke
Liu Kui, Wang Ling, Pang Tao
DOI: 10.1016/S1875-5364(24)60712-0
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