Latest Articles

Latest Articles have been peer-reviewed and accepted, which are not yet assigned to volumes/issues, but are citable by Digital Object Identifier (DOI).
Organ-on-a-chip in natural product research: advancing translational ADME, efficacy and safety assessment
Hao Lijun, Ge Ye, Wang Tingting, Wang Guangji, Zhang Jingwei
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Natural cyclopeptide RA-V induces ER stress and promotes HRD1-mediated c-Myc degradation to inhibit pancreatic cancer stemness
Jiang Zhuangzhuang, Wu Yingwei, Cao Feng, Wang Jianghao, Ye Shuqing, Sui Yihang, Tan Ninghua
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Levistilide A restrains myocardial fibrosis by targeting malate dehydrogenase 2
Pan Ting, Cheng Yingying, Yan Yutian, Cao Wenjia, Jiang Qingjia, Li Ping, Zeng Hao
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A santonin derivative, QX-6, alleviates ulcerative colitis by suppressing macrophage oxidative stress and inflammatory responses via modulation of ferroptosis-related signaling
Xiao Chuangmeng, Xie Xinyi, Lv Liqi, Duan Jiangling, Zhang Xiaokun, Li Yue, Wang Yanjun, Chen Hongzhuan, Sun Qingyan, Jin Jinmei, Luan Xin, Zhang Weidong
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Angeloylgomisin O from YiQiFuMai Lyophilized Injection attenuates heart failure by inhibiting endothelial-mesenchymal transition via ACE2
Dai Sufang, Huang Zixuan, Liu Jincheng, Wu Lingling, Zhao Qingfei, Gong Shuaishuai, Zhang Yuanyuan, Yu Boyang, Li Fang, Kou Junping
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Tracing a microbial vitamin from Bacteroides to metabolic health
Chen Liujun, Hartmann Phillipp
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Hydrolyzed ginsenosides of Panax notoginseng flowers attenuate alcoholic liver disease by inhibiting oxidative stress and lipid accumulation
Shen Hong, Ma Lijuan, Wang Kanghui, Zhou Junyi, Liu Jiayue, Wan Jianbo
DOI: 10.1016/S1875-5364(26)61118-1
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Berberine repurposing for clinical translation: Multi-target synergy, combinatorial approaches, and self-assembled delivery strategies
Ma Qi-Zhe, Zhang Shuo, Chai Yun, Mao Xi, Xu Ding-Qiao, Fu Rui-Jia, Tang Yu-Ping
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Parthenolide suppresses colorectal adenoma progression by restraining mast cell degranulation-associated epithelial remodeling
Liu Shunji, Li Jiazheng, Li Ting, Zhang Qinchang, Wu Rui, Zhang Tianyi, Cheng Haibo, Lv Wen, Sun Yang, Zhou Lisha
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Caftaric acid targets P2Y14R to restore macrophage mitophagy and ameliorate sepsis
Wang Yilin, Ni Shurui, Li Zhuoting, Lu Yuhe, Zheng Kai, Shang Shenglan, Zhou Mengze
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Hyodeoxycholic acid ameliorates the senescence of cholangiocyte and inflammasome activation in cholestatic liver diseases by activating mitophagy
Fan Guifang, Mei Ting, Zhang Yinghao, Qin Wenqing, Guo Mengyu, Wang Hong, Li Xin, Li Xinxin, Liu Runping
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Essential Oils from Medicine and Food Homology Species: A Review of Constituents, Extraction, Bioactivities and Encapsulation
Wu Xinyi, Cao Yuhan, Hu Qin, Chen Junxi, Qiao Hongzhi, Feng Xue
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Onyjaposides A–J: flavonoid-derived amphiphiles from Onychium japonicum with anti-adipogenic activity via SIRT1 upregulation
Song Xiuqing, Yang Zhenyu, Wang Xin, Fan Yaoyue
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Shiwei Wendan Decoction alleviates atherosclerosis by suppressing endothelial inflammatory responses through the CHIP/ICAM1 axis
Wu Qiu, Jiang Miao, Zhang Zehua, Zhu Ziqi, Zhao Jingcheng, Sun Wancheng, Alimujiang Abudureyimu, Chen Du, Wang Hongzhi, Li Zhijian, Xu Dengqiu, Xie Xuejiao
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The antidepressant effect of SNS during mid- and late-adolescence in male rats: the role of AMPAR expression in the DRN
Zhou Liuchang, Luo Jieru, Yao Diya, Miao Yi, Liu Dan, Zhong Jialong, Deng Di, Shi Yafei, Zhang Rong
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Material-Form-Dependent Pharmacology of Oral Chinese Herbal Medicines in Colorectal Cancer: From Gastrointestinal Compartments to Tumor Ecosystems
Wei Yu, Feng Tingyu, Liu Jing-Li, Wang Wei
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Modulation of the AhR-IDO1-Kyn Axis by Toad Venom-Derived Hua-chan-su Promotes Anti-Tumor Immunity in Gastric Cancer
Wang Meng, Wang Hainan, Gu Wei, Zhang Mengxiao, Zhao Cheng, Wang Chunhua, Li Binjing, Li Yueyue, Wang Manman, Li Shanshan, Cheng Hui, Luo Chuan, He Dongbing, Li Qinglin
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Breyniaionoside D from Huai yam attenuates Alzheimer’s disease-like pathological changes associated with calcium dysregulation and neuroinflammatory signaling
Zeng Mengnan, Ye Kaili, Hao Fengxiao, Gu Danli, Wang Yuanyuan, Zhu Xingyu, Feng Weisheng, Zheng Xiaoke
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Mechanistic Studies of Traditional Chinese Medicine in Brain Disorders: Integrating Brain-Centric Target Identification and Brain–Body Crosstalk
Huang Fuyue, Cai Xiaoying, Zhu Qimeng, Hui Siwen, Li Xinyuan, Sun Chengpeng, Zheng Xiao
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Sesquiterpene lactones from the traditional Chinese medicine Eupatorium lindleyanum DC. and their preliminary protective effects against nano-SiO2-induced injury
Xu Qing, Qing Mengli, Wang Chenhui, Dang Wen, Bai Xiaolin, Chen Gang, Zhou Di, Li Ning
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Mechanisms and translational targets of coronary microvascular endothelial injury in ischemic cardiomyopathy: from hypoxic stress to microenvironmental remodeling
Wang Tianen, Li Zhaoling, Shen Xiaoxuan, Chang Zhen, Luo Yalin, Sun Zijin, Zhang Zuhe, Chang, Tong Ying
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Self-Assembled Nanosystems Incorporating Traditional Chinese Medicine: Design, Function, and Therapeutic Performance
Qin Yi, Fan Yuanhe, Ye Heng, Wu Haoyuan, Zhang Qing, Zheng Caixia, Zhou Xunyong, Zhao Longshan, Guan Xuefeng
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Natural product screening strategies targeting the Nrf2 pathway: Current status, challenges, and future perspectives
Liu Haiyi, Su Erzheng, Duan Jin-ao, Xiao Ping
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Abnormal Mitochondrial Function in Cardiac Hypertrophy: From Mechanisms to Perspectives on Treatment with Traditional Chinese Medicine
Zhang Errui, Shi Junkai, Liu Guangyao, Zhu Yulong, VanDusen Nathan J., Tao Houchao, Gu Weiliang
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Natural Products Modulating Immune Checkpoints: From Medicinal Chemistry Insights to Translational Advances in Overcoming Tumor Immunotherapy Bottlenecks
Yuan Ting, Zhao Yichao, Ruan Bingxin, Chang Zhenhui, Jiang Feng
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Sasang Constitutional Phenotyping and the Evidence Gap in Precision Herbal Therapeutics: A Multi-Omics Roadmap
Amin Adnan
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Spatholobus suberectus Dunn Attenuates Hepatic Fibrogenesis by Disrupting the MFAP4 Mediated TGF-β1/LOXL1 Positive Feedback Loop
He Qingman, Yao Huan, Sui Yue, Gao Yongxiang, Chen Jianping
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Ecology-Guided and Technology-Enabled Strategies in the Discovery of Marine Natural Products for Drug Development
Feng Ran-Qi, Armel Kouame Kra Wilfried, Hao Yi, Osman Ezzat E. A., Guo Yue-Wei, Li Xu-Wen
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Multi-omics profiling elucidates the optimal cultivation time and chemical markers for animal-derived medicine Bungarus Parvus
Yu Kaiquan, Qiao Yajun, Wang Cuicui, Xu Meng, Wei Wenlong, Zhang Yesong, Li Tingwei, Bi Qirui, Zhang Jianqing, Guo Dean
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Traditional Chinese medicine-based drug delivery systems for anti-tumor therapies
Yang Lin, Wang Yani, Ye Xietao, Liu Qiaoming, Qu Ding, Chen Yan
DOI: 10.1016/S1875-5364(25)60860-0
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Research progress of small-molecule natural medicines for the treatment of ischemic stroke
Liu Kui, Wang Ling, Pang Tao
DOI: 10.1016/S1875-5364(24)60712-0
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