Latest Articles

Latest Articles have been peer-reviewed and accepted, which are not yet assigned to volumes/issues, but are citable by Digital Object Identifier (DOI).
Combining label-free quantitative proteomics and 2D-DIGE to identify the potential targets of Sini decoction acting on myocardial infarction
Feng Fei, Zhang Weiyue, Cao Yan, Lv Diya, Chai Yifeng, Guo Dandan, Chen Xiaofei
DOI: 10.1016/S1875-5364(24)60711-9
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Bisdemethoxycurcumin suppresses liver fibrosis-associated hepatocellular carcinoma via inhibiting CXCL12-induced macrophage polarization
Yuan Wei, Zeng Xinxin, Chen Bin, Yin Sihan, Peng Jing, Wang Xiong, Yuan Xingxing, Sun Kewei
DOI: 10.1016/S1875-5364(25)60871-5
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Anti-inflammatory and hepatoprotective triterpenoids from the traditional Mongolian medicine Gentianopsis barbata
Cheng Hui-Zhen, Liu Huan, Qi Xiao-Yu, Fan Yu-Zhou, Yuan Zhong-Zhu, Xu Yuan-Liang, Liu Yan-Chun, Liu Yan, Guo Kai, Li Sheng-Hong
DOI: 10.1016/S1875-5364(25)60870-3
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Compatibility of cold herb CP and hot herb AZ in Huanglian Ganjiang decoction alleviates colitis mice through M1/M2 macrophage polarization balance via PAK4-mediated glucose metabolism reprogramming
Li Yanyang, Liu Chang, Wang Yi, Chen Peiqi, Xu Shihua, Wu Yequn, Ren Lingzhi, Yu Yang, Yang Lei
DOI: 10.1016/S1875-5364(25)60869-7
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The novel combination of astragaloside IV and formononetin protects from doxorubicin-induced cardiomyopathy by enhancing fatty acid metabolism
Yu Xinyue, Han Zhaodi, Guo Linling, Deng Shaoqian, Wu Jing, Pan Qingqing, Zhong Liuyi, Zhao Jie, Hui Hui, Xu Fengguo, Zhang Zunjian, Huang Yin
DOI: 10.1016/S1875-5364(25)60868-5
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Lirispirolides A–L, a new class of sesquiterpene‐monoterpene heterodimers with anti-neuroinflammatory activity from the rare medicinal plant Liriodendron chinense
He Yuhang, Li Kexin, Wu Yufei, Jin Zexin, Hu Jinfeng, Mao Yicheng, Xiong Juan
DOI: 10.1016/S1875-5364(24)60702-8
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Diketopiperazines with anti-skin inflammation from marine-derived endophytic fungus Aspergillus sp. and configurational reassignment of aspertryptanthrins
Yang Jin, Xiong Xianmei, Gong Lizhi, Gan Fengyu, Shi Hanling, Zhu Bin, Wu Haizhen, Xin Xiujuan, Kong Lingyi, An Faliang
DOI: 10.1016/S1875-5364(24)60704-1
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Design and synthesis of novel saponin-triazole derivatives in regulation of adipogenesis
Fang Yongsheng, Zhu Zhiyun, Xie Chun, Xia Dazhen, Zhao Huimin, Wang Zihui, Lu Qian, Zhang Caimei, Xiong Wenyong, Yang Xiaodong
DOI: 10.1016/S1875-5364(25)60830-2
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Discovery of bioactive polycyclic polyprenylated acylphloroglucinol from Hypericum patulum that protects against hepatic ischemia/reperfusion injury
Tao Bo, Zhao Xiangli, Shi Zhengyi, Li Jie, Duan Yulin, Tan Xiaosheng, Chen Gang, Qi Changxing, Zhang Yonghui
DOI: 10.1016/S1875-5364(24)60710-7
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Structurally novel tryptamine-derived alkaloids from the seeds of Peganum harmala and their antiviral activities against respiratory syncytial virus
Wu Zhongnan, Zhang Yubo, Wang Guocai, Tang Qing, Li Yaolan, Xie Xiaoqing, Liang Yushen, Cheng Wen
DOI: 10.1016/S1875-5364(24)60708-9
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Profiling the chemical differences of diterpenoid alkaloids in different processed products of Aconiti Lateralis Radix Praeparata by UHPLC-LTQ-Orbitrap mass spectrometry combined with untargeted metabolomics and mass spectrometry imaging
Yu Yang, Yao Changliang, Zhang Jianqing, Huang Yong, Yao Shuai, Qu Hua, Zhang Tong, Guo Dean
DOI: 10.1016/S1875-5364(24)60707-7
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Dimeric sesquiterpenoids with anti-inflammatory activities from Inula britannica
Zhang Juan, Yan Jiankun, Dong Hongjun, Zhang Rui, Chang Jing, Feng Yanli, Xu Xinrong, Li Wei, Qiu Feng, Sun Chengpeng
DOI: 10.1016/S1875-5364(24)60692-8
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The transcriptomic-based disease network reveals synergistic therapeutic effect of total alkaloids from Coptis chinensis and total ginsenosides from Panax ginseng on type 2 diabetes mellitus
Chen Qian, Zhang Shuying, Jiang Xuanxi, Liao Jie, Shao Xin, Peng Xin, Wang Zheng, Lu Xiaoyan, Fan Xiaohui
DOI: 10.1016/S1875-5364(24)60689-8
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Facilitating microglial phagocytosis by which Jiawei Xionggui Decoction alleviates cognitive impairment via TREM2-mediated energy metabolic reprogramming
Wen Wen, Chen Jie, Xiang Junbao, Zhang Shiqi, Liu Jingru, Wang Jie, Wang Ping, Xu Shijun
DOI: 10.1016/S1875-5364(24)60688-6
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New tetrahydroanthraquinones and γ-butenolides from the fungus Auxarthron umbrinum DSM3193
Tian Ling, Liu Bingyu, Wei Qian, Zhang Chen, Shang Jiamin, Li Xiaoxue, Yang Xiuying, Wang Jinhua, Hu Youcai
DOI: 10.1016/S1875-5364(24)60684-9
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Diterpenoids and lignans from fossil Chinese medicinal succinum and their activity against renal fibrosis
Chen Yefei, Wang Yunfei, Liu Yunyun, Yan Yongming, Cheng Yongxian
DOI: 10.1016/S1875-5364(24)60683-7
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(±)-Talapyrones A−F: six pairs of dimeric polyketide enantiomers with unusual 6/6/6 and 6/6/6/5 ring systems from Talaromyces adpressus
Zheng Meijia, Zhao Xinyi, Zhou Chenxi, Liao Hong, Li Qin, Lu Yuling, Dai Bingbing, Sun Weiguang, Ye Ying, Chen Chunmei, Zhang Yonghui, Zhu Hucheng
DOI: 10.1016/S1875-5364(24)60699-0
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Traditional Chinese medicine-based drug delivery systems for anti-tumor therapies
Yang Ling, Wang Yani, ye Xietao, Liu Qiaoming, Qu Ding, Chen Yan
DOI: 10.1016/S1875-5364(25)60860-0
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New diterpenoids from Euphorbia wallichii with antioxidant activity
Yali Wang, Juan Chen, Wenshuo Zheng, Ziyan Gao, Yuxin Gan, Hua Li, Lixia Chen
DOI: 10.1016/S1875-5364(25)60859-4
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Cytotoxic anthrone–cyclopentenone heterodimers from the fungus Penicillium sp. guided by molecular networking
Huo Ruiyun, Dong Jiayu, Liu Gaoran, Shi Ying, Liu Ling
DOI: 10.1016/S1875-5364(25)60858-2
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Five new meroterpenoids from Rhododendron anthopogonoides and their anti-inflammatory activity
Li Mengtian, Kelsang Norbu, Zhao Yongqin, Li Wensen, Zhou Feng, Pema, Cui Lu, Bao Xianjie, Wang Qian, Feng Xin, Yang Minghua
DOI: 10.1016/S1875-5364(25)60850-8
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Oroxylin A inhibits UVB-induced non-melanoma skin cancer by regulating XPA degradation
Dou Renjie, Sun Jiarui, Yang Hang, Zheng Yufen, Yuan Kang, Qiang Lei, Ma Run, Liu Yunyao
DOI: 10.1016/S1875-5364(24)60660-6
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Bioactivity-guided discovery of antiviral templichalasins A‒C from the endophytic fungus Aspergillus templicola
Cai Teng, Sun Jingzu, Chen Wenxuan, He Qiang, Chen Baosong, He Yulong, Zhang Peng, Wei Yanhong, Liu Hongwei, Cai Xiaofeng
DOI: 10.1016/S1875-5364(24)60682-5
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Platycodon grandiflorus polysaccharides combined with hesperidin exerted the synergistic effect of relieving ulcerative colitis in mice by modulating PI3K/AKT and JAK2/STAT3 signaling pathways
Liu Yang, Sun Quanwei, Xu Xuefei, Li Mengmeng, Gao Wenheng, Li Yunlong, Yang Ye, Yin Dengke
DOI: 10.1016/S1875-5364(24)60647-3
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Wenxia Changfu Formula inhibits NSCLC metastasis by halting TAMs-induced epithelial-mesenchymal transition via antagonistically modulating CCL18
Bi QianYu, Wang MengRan, Luo Li, Zhang BeiYing, Lv SiYuan, Wang ZengNa, Ji XuMing
DOI: 10.1016/S1875-5364(24)60691-6
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Naturally occurring seco- and nor-polycyclic polyprenylated acylphloroglucinols: distribution, structural diversity, and biological activity
Duan Yulin, Tang Ying, Qi Changxing, Zhang Yonghui
DOI: 10.1016/S1875-5364(24)60668-0
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XiJiaQi Formula Attenuates Cognitive Dysfunction by Inhibiting Neuroinflammation and Promoting Neuroplasticity in Rats with Chronic Heart Failure (Manuscript ID: CJNM-2024-0848.R2, Accepted)
Chen Jie, Wu Xuefen, Zhang Qian, Shang Hongcai, Li Wanting, Zhou Linnan, Chu Xinyu, Xia Guiyang, Xia Huan, Wei Xiaohong, Lin Sheng
DOI: 10.1016/S1875-5364(25)60849-1
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The role of 8-oxoG and its repair systems in liver diseases progression: responsible mechanisms and promising natural products
Zheng Ying, Chen Junxin, Liu Ze, Wang Kaibo, Zhang Hao
DOI: 10.1016/S1875-5364(25)60848-X
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Bioactive triterpenoids from the tuber of Alisma orientale
Zhu Deng-Hui, Zhang Jing-Ke, Guo Peng-Li, Tao Si-Qi, Zeng Meng-Nan, Zheng Xiao-Ke, Feng Wei-Sheng
DOI: 10.1016/S1875-5364(25)60844-2
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Paclitaxel Anti-Cancer Therapeutics: From Discovery to Clinical Use
Yu Haizheng, Lan Fen, Zhuang Yuan, Li Qizhang, Zhang Lianqing, Tian Hongchang, Bu Xiao, Chen Ruibing, Gao Yingying, Wang Zhuo, Zhang Lei
DOI: 10.1016/S1875-5364(25)60833-8
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Mechanism and research progress of improving cartilage injury based on the combination of active ingredients in traditional Chinese medicine and biomaterials (Accepted)
Li Jiali, Gao Yuan, Zhang Li, Hou Quanjie, Fu Xinru, Song Jipeng, Liu Yiming, Shen Yunheng, Xu Xike, Ding Xia, Feng Yu, Chen Xin, Zu Xianpeng
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Advances in the study of pharmacotherapy for addiction to naturally-derived psychoactive substances
Xie Kexin, Xiao Deli, Xu Peng, Shen Haowei, Di Bin
DOI: 10.1016/S1875-5364(25)60831-4
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Research progress on polysaccharides from medicine and food homology materials in functional foods
Hu Dejun, Zhang Yifan, Li Boyao, Cao Chongjiang
DOI: 10.1016/S1875-5364(25)60829-6
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The potential therapeutic role of ginsenosides on fibrosis-associated diseases: A review on molecular mechanisms and call for further research
WEI Mengguang, ZHANG Yue, SUN Xiaomeng, QI Lianwen, LIU Qun
DOI: 10.1016/S1875-5364(25)60817-X
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Emerging evidence of inter-organ interaction on drug transporters under liver injury
JIANG Ling, DENG Ying, MU Ruijing, FENG Wenke, LIU Xiaonan, LIU Li
DOI: 10.1016/S1875-5364(24)60729-6
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Host-Microbe Co-metabolism System as Potential Targets: the Promising Way for Natural Medicine to Treat Atherosclerosis
Wang Yun, Zhou Ziwei, Hao Haiping, Cao Lijuan
DOI: 10.1016/S1875-5364(24)60749-1
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Advancements and Applications in Radiopharmaceutical Therapy
Wang Shiya, Cao Mingyi, Chen Yifei, Lin Jingjing, Li Jiahao, Wu Xinyu, Dai Zhiyue, Pan Yuhan, Liu Xiao, Liu Xian, Lin Liang-Ting, Wu Jianbing, Liu Ji, Zhong Qifeng, Yuan Zhenwei
DOI: 10.1016/S1875-5364(24)60747-8
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Leveraging Microbial Natural Products for Pharmaceutical Innovation: A Vision of Inspiration and Future Prospects
YANG Jun-Biao, WANG Ji-Wen, LIU Meng-Qun, ZHOU Xu-Zhe, Feng Dong, JIANG Han-Xiang, LIU Xin-Na, Chen Lu, WANG Ying
DOI: 10.1016/S1875-5364(24)60713-2
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Combination of Astragalus-Salvia and Ophiopogon-Dendrobium herb pairs alleviates Sjögren’s Syndrome via inhibiting the JAK1/STAT3 and PI3K/AKT pathways in NOD/Ltj mice
SUN Peng, ZHU Li-Li, YU Yang, HU Si-Jing, SHAN Meng-Yi, ZHAO Xuan, WANG Xin-Chang, ZHANG Qiao-Yan, QIN Lu-Ping
DOI: 10.1016/S1875-5364(24)60743-0
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First-in-class drug Oroxylin A tables for treating hepatic and gastrointestinal disorders: From preclinical development to clinical research
Luo Chengju, Li Xuhong, Gao Yuan, Yang Junyi, Fang Weiming, Wei Libin
DOI: 10.1016/S1875-5364(24)60740-5
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Natural endogenous material-based vehicles for delivery of macromolecular drugs
LU An, DU Kang, WANG Meng, ZHU Zehang, LEI Lei, SHI Yujie
DOI: 10.1016/S1875-5364(24)60738-7
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Research Progress of Natural Saccharides and Their Derivatives as Drug Delivery Materials
WEI Yuning, KONG Weiwen, LIU Wenjuan, DONG Zirong, YANG Peiheng, TAO Juan, WEI Zibo, YANG Jinlong, QI Jianping
DOI: 10.1016/S1875-5364(24)60737-5
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TCM network pharmacology: New perspective integrating network target with artificial intelligence and multi-modal multi-omics technologies
Wang Ziyi, Zhang Tingyu, Wang Boyang, Li Shao
DOI: 10.1016/S1875-5364(24)60734-X
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Azaphilone derivatives with RANKL-induced osteoclastogenesis inhibition from the mangrove endophytic fungus Diaporthe sp.
Lin Miaoping, Tan Yanhui, Lu Humu, Feng Yuyao, Li Min, Gao Chenghai, Liu Yonghong, Luo Xiaowei
DOI: 10.1016/S1875-5364(24)60730-2
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Ten New Lignans with Anti-inflammatory Activities from the Leaves of Illicium dunnianum
LI Ting, HE Xiaoqiang, PAN Dabo, ZENG Xiaochun, ZENG Siying, WANG Zhenzhong, YAO Xinsheng, XIAO Wei, LI Haibo, YU Yang
DOI: 10.1016/S1875-5364(24)60718-1
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TSZAF monomer combination downregulates the Wnt/β-catenin signaling pathway and inhibits neutrophil recruitment to prevent lung cancer metastasis
Yu Pan, Yao Jialiang, Zhang Long, Wang Yanhong, Lu Xinyi, Liu Jiajun, Que Zujun, Liu Yao, Ba Qian, Liu Jiwei, Wu Yan, Tian Jianhui
DOI: 10.1016/S1875-5364(24)60717-X
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Jasurolignoside from Ilex pubescens exerts a therapeutic effect on acute lung injury in vitro and in vivo by binding to TLR4
Han Shan, Vong Chi Teng, He Jia, Wang Qin-Qin, Fan Qiumei, Li Siyuan, Li Jilang, Liao Min, Yang Shilin, Yuan Renyikun, Gao Hongwei
DOI: 10.1016/S1875-5364(24)60715-6
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Research Progress on New Techniques and Methods for Identifying Active Ingredients in Traditional Chinese Medicine
ZHANG Jiaxin, ZHU Xinhao, ZHANG Chaofeng, ZHANG Wangning, TIAN Jiangwei
DOI: 10.1016/S1875-5364(24)60714-4
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Research progress of small-molecule natural medicines for the treatment of ischemic stroke
Liu Kui, Wang Ling, Pang Tao
DOI: 10.1016/S1875-5364(24)60712-0
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Structurally diverse terpenoids from Pseudotsuga brevifolia and their inhibitory effects against ACL and ACC1 enzymes
ZHOU Peng-Jun, ZHAO Ze-Yu, ZANG Yi, XIONG Juan, CHOO Yeun-Mun, LI Jia, HU Jin-Feng
DOI: 10.1016/S1875-5364(24)60709-0
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Recent advances in peptide-based therapy: Challenges, strategies and future perspectives
YANG Qimeng, HU Zhipeng, JIANG Hongyu, WANG Jialing, HAN Han, SHI Wei, QIAN Hai
DOI: 10.1016/S1875-5364(24)60697-7
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Natural products targeting NLRP3 inflammasome for metabolic dysfunction-associated fatty liver disease: The known unknowns
Meng Jiahui, Wang Qiqi, Wang Haopeng, Shen Xuange, Qin Tingting, Zhao Wen, Li Haixia, Yuan Ziqiao
DOI: 10.1016/S1875-5364(24)60695-3
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Isodons A-H, seco-abietane and abietane-type diterpenoids from Isodon lophanthoides: isolation, structural elucidation, and anticholestatic activity
Zhou Hui-Ling, Han Ming-Zhu, Nan Miao-Miao, Leng Ying-Rong, Huang Wei-Ming, Ye Sheng-Tao, Kong Ling-Yi, Xu Wen-Jun, Zhang Hao
DOI: 10.1016/S1875-5364(24)60686-2
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Deciphering the therapeutic potential and mechanisms of Artemisia argyit essential oil on flagellum-mediated Salmonella infections
Linlin Ding, Lei Xu, Na Hu, Jianfeng Wang, Jiazhang Qiu, Qingjie Li, Xuming Deng
DOI: 10.1016/S1875-5364(24)60703-X
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Identification and biomimetic synthesis of iphionanes and cyperanes from Artemisia hedinii and their anti-hepatic fibrosis activity
LIU Xiaofei, WANG Xing, TANG Chunping, KE ChangQiang, HU Bintao, YAO Sheng, YE Yang
DOI: 10.1016/S1875-5364(24)60701-6
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Diphenylemestrins A−E: Diketopiperazine-Diphenyl Ether Hybrids from Aspergillus nidulans
Fu Aimin, Li Qin, Xiao Yang, Dong Jiaxin, Peng Yuanyang, Chen Yu, Tong Qingyi, Chen Chunmei, Zhang Yonghui, Zhu Hucheng
DOI: 10.1016/S1875-5364(24)60662-X
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Withanolide derivatives from Physalis angulata var. villosa and their cytotoxic activities
Wang Peng, Yang Jue, Zhang Yu, Jin Jun, Chen Mei-Jun, Hao Xiao-Jiang, Yuan Chun-Mao, Yi Ping
DOI: 10.1016/S1875-5364(24)60625-4
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Natural Diosmin Alleviating Obesity and NAFLD by Regulating AMPK Pathway
Liu Can, Hao Siyu, Zhang Mengdi, Wang Xueyu, Chu Baiwang, Wen Tingjie, Dang Ruoyu, Sun Hua
DOI: 10.1016/S1875-5364(24)60609-6
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Harmonizing tradition and technology: liposomal nanocarriers unlocking the power of natural herbs in Traditional Chinese Medicine
SHAW IBRAHIM, ARYEE AARON ALBERT, ALI YIMER SEID, BOAFO GEORGE FRIMPONG, TIAN JINGJING, MLAMBO RONALD, TAN SONGWEN, CHEN CHUANPIN
DOI: 10.1016/S1875-5364(24)60552-2
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Kai-Xin-San Alleviated Neurodegeneration by Reducing Neuroinflammation and Rebalancing Intestinal Flora in APP/PS1 mice
Li Meixian, Li Jiaqi, Wei Dongyun, Wang Qi, Jian Wenxuan
DOI: 10.1016/S1875-5364(23)60513-8
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Tu-Xian decoction ameliorates diabetic cognitive impairment by inhibiting DAPK-1
DOI: 10.1016/S1875-5364(23)60406-6
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Isolation and Biological Activity of Seven New Drimane-Type Sesquiterpenoids from an Earwig-Associated Aspergillus sp. NF2396
Salman Khan, ZHU Hong-Jie, SUN Zi-Qian, Li Yi-Lin, WANG Lan, WANG Rong, GUO Zhi-Kai, JIAO Rui-Hua
DOI: 10.1016/S1875-5364(22)60207-3
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Liver metabonomics study on the protective effect of glycyrrhetinic acid against realgar-induced liver injury
Huo Taoguang, Fang Ying, Zhang Yinghua, Feng Cong, Jiang Hong
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