[1]
|
Lam FFY, Yeung JHK, Cheung JHY, et al. Pharmacological evidence for calcium channel inhibition by Danshen (Salvia miltiorrhiza) on rat isolated femoral artery[J]. J Cardiovasc Pharmacol, 2006, 47(1):139-145. |
[2]
|
Editorial Committee of Flora of China. Flora of China[M]. Science Press, 1994:212. |
[3]
|
Zhou Y, Li W, Xu L, et al. In Salvia miltiorrhiza, phenolic acids possess protective properties against amyloid -induced cytotoxicity, and tanshinones act as acetylcholinesterase inhibitors[J]. Environ Toxicol Pharmacol, 2011, 31(3):443-452. |
[4]
|
Wong KKK, Ho MTW, Lin HQ, et al. Cryptotanshinone, an acetylcholinesterase inhibitor from Salvia miltiorrhiza, ameliorates scopolamine-induced amnesia in Morris water maze task[J]. Planta Med, 2010, 76(3):228-234. |
[5]
|
Zhang HN, An CN, Pu XP. Protocatechuic acid inhibits neurotoxicity induced by MPTP in vivo[J]. Neurosci Lett, 2010, 474(2):99-103. |
[6]
|
Kang DG, Oh H, Sohn EJ, et al. Lithospermic acid B isolated from Salvia miltiorrhiza ameliorates ischemia/reperfusioninduced renal injury in rats[J]. Life Sci, 2004, 75(15):1801-1816. |
[7]
|
Lin YL, Wu CH, Luo MH, et al. In vitro protective effects of salvianolic acid B on primary hepatocytes and hepatic stellate cells[J]. J Ethnopharmacol, 2006, 105(1):215-222. |
[8]
|
Wu Z, Wen T, Tan Y, et al. Effects of salvianolic acid A on oxidative stress and liver injury induced by carbon tetrachloride in rats[J]. Basic Clin Pharmacol, 2007, 100(2):115-120. |
[9]
|
Zhang HS, Wang SQ. Salvianolic acid B from Salvia miltiorrhiza inhibits tumor necrosis factor- (TNF-)-induced MMP-2 upregulation in human aortic smooth muscle cells via suppression of NAD(P)H oxidase-derived reactive oxygen species[J]. J Mol Cell Cardiol, 2006, 41(1):138-148. |
[10]
|
Tian X, Xue W, Ding X. Application of Danshen injection on early stage of renal transplantation[J]. Chin J Integr Med, 2005, 25(5):404-407. |
[11]
|
Cheng TO. Danshen:a popular Chinese cardiac herbal drug[J]. J Am Coll Cardiol, 2006, 47(7):1498-1498. |
[12]
|
Zhou L, Zuo Z, Chow MSS. Danshen:an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use[J]. J Clin Pharmacol, 2005, 45(12):1345-1359. |
[13]
|
Editorial Committee of Flora of Anhui. Flora of Anhui[M]. Anhui Science Technology Publishing House, 1986:276. |
[14]
|
Yang Y, Wang ZR, Xu BL, et al. A comparative study of cyclosporin A, Danshen and verapamil on inhibiting epithelium cell proliferation[J]. Chin Pharmacol Bull, 1997, 13(4):370-372. |
[15]
|
Howes MJR, Houghton PJ. Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function[J]. Pharmacol Biochem Behav, 2003, 75(3):513-527. |
[16]
|
Liu C, Shi W, Sun L, et al. Effects of radix Salvia miltiorrhiza on visceral pain discharges in the posterior nucleus of the thalamus in cats[J]. Chin J Chin Mater Med, 1990, 15(2):112-115. |
[17]
|
Gao S, Liu Z, Li H, et al. Cardiovascular actions and therapeutic potential of tanshinone IIA[J]. Atherosclerosis, 2012, 220(1):3-10. |
[18]
|
Liang Q, Liang ZS, Wang JR, et al. Essential oil composition of Salvia miltiorrhiza flower[J]. Food Chem, 2009, 113(2):592-594. |
[19]
|
Ryu SY, Lee CO, Choi SU. In vitro cytotoxicity of tanshinones from Salvia miltiorrhiza[J]. Planta Med, 1997, 63(4):339-342. |
[20]
|
Ryu SY, No Z, Kim SH, et al. Two novel abietane diterpenes from Salvia miltiorrhiza[J]. Planta Med, 1997, 63(1):44-46. |
[21]
|
Yang B, Qian M, Qin G, et al. Studies on the active principles of Danshen. V. isolation and structures of przewaquinone A and prezewaquinone B[J]. Acta Pharm Sin, 1981, 16(11):837-841. |
[22]
|
Chang HM, Cheng KP, Choang TF, et al. Structure elucidation and total synthesis of new tanshinones isolated from Salvia miltiorrhiza Bunge (Danshen)[J]. J Org Chem, 1990, 55(11):3537-3543. |
[23]
|
Wang X, Morris-Natschke SL, Lee KH. New developments in the chemistry and biology of the bioactive constituents of Tanshen[J]. Med Res Rev, 2007, 27(1):133-148. |
[24]
|
Luo H, Wu B, Wu M, et al. Pigments from Salvia miltiorrhiza[J]. Phytochemistry, 1985, 24(4):815-817. |
[25]
|
Cheng Y, Fong S, Chang H. Protective action of Salvia miltiorrhiza aqueous extract on chemically induced acute myocardial ischemia in rats[J]. Chin J Integr Med, 1990, 10(10):609-611. |
[26]
|
Yang M, Liu A, Guan S, et al. Characterization of tanshinones in the roots of Salvia miltiorrhiza (Danshen) by high performance liquid chromatography with electrospray ionization tandem mass spectrometry[J]. Rapid Commun Mass Spectrom, 2006, 20(8):1266-1280. |
[27]
|
An LK, Bu XZ, Wu HQ, et al. Reaction of tanshinones with biogenic amine metabolites in vitro[J]. Tetrahedron, 2002, 58(52):10315-10321. |
[28]
|
Lin H, Chang W, Chen C. Phytochemical and pharmacological study on Salvia miltiorrhiza (VI)-cytotoxic activity of tanshinones[J]. Chin Pharm J, 1995, 47(1):77-80. |
[29]
|
Feng B, Li S. Studies on the chemical components of Danshen (Salvia miltiorrhiza Bunge)[J]. Acta Pharm Sin, 1980, 15(8):489-494. |
[30]
|
Sun A, Zhang Y, Li A, et al. Extraction and preparative purification of tanshinones from Salvia miltiorrhiza Bunge by high-speed counter-current chromatography[J]. J Chromatogr B, 2011, 879(21):1899-1904. |
[31]
|
Ikeshiro Y, Hashimoto I, Iwamoto Y, et al. Diterpenoids from Salvia miltiorrhiza[J]. Phytochemistry, 1991, 30(8):2791-2792. |
[32]
|
Kong DY, Liu XJ. Structure of dihydroisotanshinone I of Danshen[J]. Acta Pharm Sin, 1984, 19(10):755-756. |
[33]
|
Hu P, Liang QL, Luo GA, et al. Multi-component HPLC fingerprinting of radix Salvia miltiorrhiza and its LC-MS-MS identification[J]. Chem Pharm Bull, 2005, 53(6):677-683. |
[34]
|
Zhang KQ, Bao Y, Wu P, et al. Antioxidative components of Tanshen (Salvia miltiorhiza Bunge)[J]. J Agric Food Chem, 1990, 38(5):1194-1197. |
[35]
|
Ma Z, Zhang M, Song Z. Characterization of tanshinones with quinone reductase induction activity from radix Salvia miltiorrhiza by liquid chromatography/tandem mass spectrometry[J]. Rapid Commun Mass Spectrom, 2009, 23(18):2857-2866. |
[36]
|
Lin H, Chang W. Phytochemical and pharmacological study on Salvia miltiorrhiza (I)-isolation of new tanshinones[J]. Chin Pharm J, 1991, 43(1):11-17. |
[37]
|
Nagy G, Gnther G, Mth I, et al. Diterpenoids from Salvia glutinosa, S. austriaca, S. tomentosa and S. verticillata roots[J]. Phytochemistry, 1999, 52(6):1105-1109. |
[38]
|
Sun J, Huang SH, Tan BKH, et al. Effects of purified herbal extract of Salvia miltiorrhiza on ischemic rat myocardium after acute myocardial infarction[J]. Life Sci, 2005, 76(24):2849-2860. |
[39]
|
Li YG, Song L, Liu M, et al. Advancement in analysis of Salvia miltiorrhiza radix et rhizoma (Danshen)[J]. J Chromatogr A, 2009, 1216(11):1941-1953. |
[40]
|
Lee AR, Wu WL, Chang WL, et al. Isolation and bioactivity of new tanshinones[J]. J Nat Prod, 1987, 50(2):157-160. |
[41]
|
Han YM, Oh H, Na M, et al. PTP1B inhibitory effect of abietane diterpenes isolated from Salvia miltiorrhiza[J]. Biol Pharm Bull, 2005, 28(9):1795-1797. |
[42]
|
Danheiser RL, Casebier DS, Loebach JL. Total synthesis of Danshen diterpenoid quinones[J]. Tetrahedron Lett, 1992, 33(9):1149-1152. |
[43]
|
Luo HW, Sun XR, Niwa M. Diterpenoids from Salvia paramiltiorrhiza[J]. ChemInform, 1995, 26(7):2473-2479. |
[44]
|
Luo H, Wu B, Wu M, et al. Isolation and structure of danshenxinkun D[J]. Acta Pharm Sin, 1985, 20(7):542-544. |
[45]
|
Harrison LJ, Asakawa Y. 18-Oxoferruginol from the leaf of Torreya nucifera[J]. Phytochemistry, 1987, 26(4):1211-1212. |
[46]
|
Gao J, Han G. Cytotoxic abietane diterpenoids from Caryopteris incana[J]. Phytochemistry, 1997, 44(4):759-761. |
[47]
|
Dat NT, Jin X, Lee JH, et al. Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1[J]. J Nat Prod, 2007, 70(7):1093-1097. |
[48]
|
Lu X, Luo H, Niwa M. Trijuganone A and B:two new phenanthrenequinones from roots of Salvia trijuga[J]. Planta Med, 1990, 56(1):87-88. |
[49]
|
Jiang RW, Lau KM, Hon PM, et al. Chemistry and biological activities of caffeic acid derivatives from Salvia miltiorrhiza[J]. Curr Med Chem, 2005, 12(2):237-246. |
[50]
|
Ai CB, Li L. Salvianolic acid D and E, two new depsides from Salvia miltiorrhiza[J]. Planta Med, 1992, 58(2):197-199. |
[51]
|
Li L, Tan R, Chen W. Salvianolic acid A, a new depside from roots of Salvia miltiorrhiza[J]. Planta Med, 1984, 50(3):227-228. |
[52]
|
Kang HS, Chung HY, Jung JH, et al. Antioxidant effect of Salvia miltiorrhiza[J]. Arch Pharm Res, 1997, 20(5):496-500. |
[53]
|
Ai CB, Li LN. Synthesis of tetramethyl salvianolic acid F and trimethyl przewalskinic acid A[J]. Chin Chem Lett, 1996, 7(5):427-30. |
[54]
|
Kohda H, Takeda O, Tanaka S, et al. Isolation of inhibitors of adenylate cyclase from Danshen, the root of Salvia miltiorrhiza[J]. Chem Pharm Bull, 1989, 37(5):1287-1290. |
[55]
|
Ai C, Li L. Salvianolic acid G, a caffeic acid dimer with novel tetracyclic skeleton[J]. Chin Chem Lett, 1991, 2:17-18. |
[56]
|
Chang JY, Chang CY, Kuo CC, et al. Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and-resistant human tumor cells[J]. Mol Pharmacol, 2004, 65(1):77-84. |
[57]
|
Kang HS, Chung HY, Byun DS, et al. Further isolation of antioxidative (+)-1-hydroxypinoresinol-1-O--D-glucoside from the rhizome of Salvia miltiorrhiza that acts on peroxynitrite, total ROS and 1, 1-diphenyl-2-picrylhydrazyl radical[J]. Arch Pharm Res, 2003, 26(1):24-27. |
[58]
|
Ai CB, Li LN. Stereostructure of salvianolic acid B and isolation of salvianolic acid C from Salvia miltiorrhiza[J]. J Nat Prod, 1988, 51(1):145-149. |
[59]
|
Zhu Z, Zhang H, Zhao L, et al. Rapid separation and identification of phenolic and diterpenoid constituents from radix Salvia miltiorrhiza by high-performance liquid chromatography diode-array detection, electrospray ionization time-offlight mass spectrometry and electrospray ionization quadrupole ion trap mass spectrometry[J]. Rapid Commun Mass Spectrom, 2007, 21(12):1855-1856. |
[60]
|
Li LN. Water soluble active components of Salvia miltiorrhiza and related plants[J]. J Chin Pharm Sci, 1997, 6(2):57-64. |
[61]
|
Zhang HJ, Li LN. Salvianolic acid I:a new depside from Salvia cavaleriei[J]. Planta Med, 1994, 60(1):70-72. |
[62]
|
Ai CB, Deng QH, Song WZ, et al. Salvianolic acid J, a depside from Salvia flava[J]. Phytochemistry, 1994, 37(3):907-908. |
[63]
|
Yokozawa T, Chung H, Oura H, et al. Isolation of a renal function facilitating constituent from the Oriental drug, Salvia miltiorrhiza radix[J]. Nippon Jinzo Gakkai Shi, 1989, 31(10):1091-1098. |
[64]
|
Tanaka T, Morimoto S, Nonaka G, et al. Magnesium and ammonium-potassium lithospermates B, the active principles having a uremia-preventive effect from Salvia miltiorrhiza[J]. Chem Pharm Bull, 1989, 37(2):340-344. |
[65]
|
Xu J, Tan T, Janson JC. One-step simultaneous purification of three water-soluble constituents in crude extracts from Danshen by adsorption chromatography on oligo--cyclodextrin substituted agarose gel media[J]. Process Biochem, 2007, 42(3):480-485. |
[66]
|
Yang Z, Hon PM, Chui KY, et al. Naturally occurring benzofuran:isolation, structure elucidation and total synthesis of 5-(3-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyp henyl)-3-benzo[b] furancarbaldehyde, a novel adenosine A1 receptor ligand isolated from Salvia miltiorrhiza Bunge (Danshen)[J]. Tetrahedron Lett, 1991, 32(18):2061-2064. |
[67]
|
Don MJ, Shen CC, Syu WJ, et al. Cytotoxic and aromatic constituents from Salvia miltiorrhiza[J]. Phytochemistry, 2006, 67(5):497-503. |
[68]
|
Wang X, Bastow KF, Sun CM, et al. Antitumor agents. 239. isolation, structure elucidation, total synthesis, and anti-breast cancer activity of neo-tanshinlactone from Salvia miltiorrhiza[J]. J Med Chem, 2004, 47(23):5816-5819. |
[69]
|
Ji XY, Tan B, Zhu YZ. Salvia miltiorrhiza and ischemic diseases[J]. Acta Pharmacol Sin, 2000, 21(12):1089-1094. |
[70]
|
Chan K, Chui S, Wong D, et al. Protective effects of danshensu from the aqueous extract of Salvia miltiorrhiza (Danshen) against homocysteine-induced endothelial dysfunction[J]. Life Sci, 2004, 75(26):3157-3171. |
[71]
|
Liu HB, Xu J, Peng Y, et al. Targets of Danshen's active components for activating blood circulation activities[J]. Acta Phys-Chim Sin, 2010, 26(1):199-205. |
[72]
|
Morse D, Choi AM. Heme oxygenase-1:the emerging molecule has arrived[J]. Am J Resp Cell Mol, 2002, 27(1):8-16. |
[73]
|
Lee SE, Jeong SI, Yang H, et al. Extract of Salvia miltiorrhiza (Danshen) induces Nrf2-mediated heme oxygenase-1 expression as a cytoprotective action in RAW264.7 macrophages[J]. J Ethnopharmacol, 2011, 139(2):541-548. |
[74]
|
Hung YC, Wang PW, Pan TL, et al. Proteomic screening of antioxidant effects exhibited by radix Salvia miltiorrhiza aqueous extract in cultured rat aortic smooth muscle cells under homocysteine treatment[J]. J Ethnopharmacol, 2009, 124(3):463-474. |
[75]
|
Mao H, Zhang H, Wang H, et al. Dual effects of lipophilic extract of Salvia miltiorrhiza (Danshen) on catecholamine secretion in cultured bovine adrenal medullary cells[J]. J Ethnopharmacol, 2009, 125(1):59-67. |
[76]
|
Zhang JP, Zhang YY, Zhang Y, et al. Salvia miltiorrhiza (Danshen) injection ameliorates iron overload-induced cardiac damage in mice[J]. Planta Med, 2013, 79(9):744-752. |
[77]
|
Xing YL, Zhou Z, Zhong ZY, et al. Protocatechuic aldehyde inhibits lipopolysaccharide-induced human umbilical vein endothelial cell apoptosis via regulation of caspase-3[J]. Phytother Res, 2012, 26(9):1334-1341. |
[78]
|
Jin UH, Kang SK, Suh SJ, et al. Inhibitory effect of Salvia miltiorrhia Bunge on matrix metalloproteinase-9 activity and migration of TNF--induced human aortic smooth muscle cells[J]. Vasc Pharmacol, 2006, 44(5):345-353. |
[79]
|
Ross R. The pathogenesis of atherosclerosis:a perspective for the 1990s[J]. Nature, 1993, 362(6423):801-809. |
[80]
|
Chen L, Wang W, Wang Y. Inhibitory effects of lithospermic acid on proliferation and migration of rat vascular smooth muscle cells[J]. Acta Pharmacol Sin, 2009, 30(9):1245-1252. |
[81]
|
Li X, Du JR, Yu Y, et al. Tanshinone IIA inhibits smooth muscle proliferation and intimal hyperplasia in the rat carotid ballooninjured model through inhibition of MAPK signaling pathway[J]. J Ethnopharmacol, 2010, 129(2):273-279. |
[82]
|
Chang CC, Chu CF, Wang CN, et al. The anti-atherosclerotic effect of tanshinone IIA is associated with the inhibition of TNF--induced VCAM-1, ICAM-1 and CX3CL1 expression[J]. Phytomedicine, 2014, 21(3):207-216. |
[83]
|
Hung YC, Wang PW, Pan TL. Functional proteomics reveal the effect of Salvia miltiorrhiza aqueous extract against vascular atherosclerotic lesions[J]. BBA-Proteins Proteom, 2010, 1804(6):1310-1321. |
[84]
|
Fang Z, Lin R, Yuan B, et al. Tanshinone IIA inhibits atherosclerotic plaque formation by down-regulating MMP-2 and MMP-9 expression in rabbits fed a high-fat diet[J]. Life Sci, 2007, 81(17):1339-1345. |
[85]
|
Zhang N, Zou H, Jin L, et al. Biphasic effects of sodium danshensu on vessel function in isolated rat aorta[J]. Acta Pharmacol Sin, 2010, 31(4):421-428. |
[86]
|
Yang Y, Cai F, Li PY, et al. Activation of high conductance Ca2+ -activated K+ channels by sodium tanshinone IIA sulfonate (DS-201) in porcine coronary artery smooth muscle cells[J]. Eur J Pharmacol, 2008, 598(1):9-15. |
[87]
|
Huang Y, Liu M, Dong M, et al. Effects of sodium tanshinone II A sulphonate on hypoxic pulmonary hypertension in rats in vivo and on Kv2.1 expression in pulmonary artery smooth muscle cells in vivo[J]. J Ethnopharmacol, 2009, 125(3):436-443. |
[88]
|
Ji W, Gong B. Hypolipidemic activity and mechanism of purified herbal extract of Salvia miltiorrhiza in hyperlipidemic rats[J]. J Ethnopharmacol, 2008, 119(2):291-298. |
[89]
|
Li C, Dong X, Fan X, et al. Aqueous extract of Danshen (Salvia miltiorrhiza Bunge) protects ovariectomized rats fed with high-fat diet from endothelial dysfunction[J]. Menopause, 2013, 20(1):100-109. |
[90]
|
Li Z, Zhu L, Huang B. Effects of purified herbal extract of Salvia miltiorrhiza on lipid profile in hyperlipidemic patients[J]. J Geriatr Cardiol, 2009, 6(2):99-101. |
[91]
|
Nagaya N, Fujii T, Iwase T, et al. Intravenous administration of mesenchymal stem cells improves cardiac function in rats with acute myocardial infarction through angiogenesis and myogenesis[J]. Am J Physiol-Heart C, 2004, 287(6):2670-2676. |
[92]
|
Tong Y, Xu W, Han H, et al. Tanshinone IIA increases recruitment of bone marrow mesenchymal stem cells to infarct region via up-regulating stromal cell-derived factor-1/CXC chemokine receptor 4 axis in a myocardial ischemia model[J]. Phytomedicine, 2011, 18(6):443-450. |
[93]
|
Li YJ, Duan CL, Liu JX, et al. Pro-angiogenic actions of salvianolic acids on in vitro cultured endothelial progenitor cells and chick embryo chorioallantoic membrane model[J]. J Ethnopharmacol, 2010, 131(3):562-566. |
[94]
|
Li YJ, Duan CL, Liu JX. Salvianolic acid A promotes the acceleration of neovascularization in the ischemic rat myocardium and the functions of endothelial progenitor cells[J]. J Ethnopharmacol, 2014, 151(1):218-227. |
[95]
|
Jin YC, Kim CW, Kim YM, et al. Cryptotanshinone, a lipophilic compound of Salvia miltiorrriza root, inhibits TNF--induced expression of adhesion molecules in HUVEC and attenuates rat myocardial ischemia/reperfusion injury in vivo[J]. Eur J Pharmacol, 2009, 614(1):91-97. |
[96]
|
Liang XY, Li HN, Yang XY, et al. Effect of Danshen aqueous extract on serum hs-CRP, IL-8, IL-10, TNF- levels, and IL-10 mRNA, TNF- mRNA expression levels, cerebral TGF-1 positive expression level and its neuroprotective mechanisms in CIR rats[J]. Mol Biol Rep, 2013, 40(4):3419-3427. |
[97]
|
Abbott NJ. Inflammatory mediators and modulation of blood brain barrier permeability[J]. Cell Mol Neurobiol, 2000, 20(2):131-147. |
[98]
|
Ballabh P, Braun A, Nedergaard M. The blood-brain barrier:an overview:structure, regulation, and clinical implications[J]. Neurobiol Dis, 2004, 16(1):1-13. |
[99]
|
Tang C, Xue H, Bai C, et al. The effects of tanshinone IIA on blood-brain barrier and brain edema after transient middle cerebral artery occlusion in rats[J]. Phytomedicine, 2010, 17(14):1145-1149. |
[100]
|
Kitagawa K. CREB and cAMP response element-mediated gene expression in the ischemic brain[J]. FEBS J, 2007, 274(13):3210-3217. |
[101]
|
Conkright MD, Canettieri G, Screaton R, et al. TORCs:transducers of regulated CREB activity[J]. Mol Cell, 2003, 12(2):413-423. |
[102]
|
Iourgenko V, Zhang W, Mickanin C, et al. Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells[J]. Sci Signal, 2003, 100(21):12147-121 |