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Chemical profiling of Jinqi Jiangtang tablets by HPLC-ESI-Q-TOF/MS

Chemical profiling of Jinqi Jiangtang tablets by HPLC-ESI-Q-TOF/MS

  • 摘要: AIM:To profile the chemical constituents in Jinqi Jiangtang tablets.METHOD:Based on the chromatographic retention behavior,fragmentation patterns of chemical components,and published literatures,a high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry(HPLC-ESI-Q-TOF/MS) method was established to characterize and identify components in Jinqi Jiangtang tablets.RESULTS:A total of 52 chemical compounds,including eight iridoid glycosides,seven phenolic acids,twelve alkaloids,six flavonoids,and nineteen saponins,were identified in Jinqi Jiangtang tablets.CONCLUSION:The established method could serve as a powerful tool for structural characterization and quality control of this Chinese herbal preparation.

     

    Abstract: AIM:To profile the chemical constituents in Jinqi Jiangtang tablets.METHOD:Based on the chromatographic retention behavior,fragmentation patterns of chemical components,and published literatures,a high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry(HPLC-ESI-Q-TOF/MS) method was established to characterize and identify components in Jinqi Jiangtang tablets.RESULTS:A total of 52 chemical compounds,including eight iridoid glycosides,seven phenolic acids,twelve alkaloids,six flavonoids,and nineteen saponins,were identified in Jinqi Jiangtang tablets.CONCLUSION:The established method could serve as a powerful tool for structural characterization and quality control of this Chinese herbal preparation.

     

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