Abstract:
Five new flavonoid derivatives, cajavolubones A–E (
1 –
5 ), along with six known analogues (
6 –
11 ) were isolated from
Cajanus volubilis, and their structures were elucidated by spectroscopic analysis and quantum chemical calculations. Cajavolubones A and B (
1 and
2 ) were identified as two geranylated chalcones. Cajavolubone C (
3 ) was a prenylated flavone, while cajavolubones D and E (
4 and
5 ) were two prenylated isoflavanones. Compounds
3 ,
8 ,
9 and
11 displayed cytotoxicity against HCT-116 cancer cell line.