YEON Jae-Ho, CHENG Liang, HE Quan-Quan, KONG Ling-Yi. A lignin glycoside and a nortriterpenoid from Kadsura coccinea[J]. Chinese Journal of Natural Medicines, 2014, 12(10): 782-785.
Citation: YEON Jae-Ho, CHENG Liang, HE Quan-Quan, KONG Ling-Yi. A lignin glycoside and a nortriterpenoid from Kadsura coccinea[J]. Chinese Journal of Natural Medicines, 2014, 12(10): 782-785.

A lignin glycoside and a nortriterpenoid from Kadsura coccinea

  • AIM:To study the chemical constituents of the roots and stem bark of Kadsura coccinea.METHOD:Compounds were isolated by column chromatography on silica gel and Sephadex LH-20,and finally purified by prep-HPLC.Their structures were elucidated by extensive spectroscopic methods,including 1D-and 2D-NMR,and HR-ESI-MS.RESULTS:Two compounds were determined as(7'S,8'S,8R)-(8,8')-dimethyl-4,4'-dihydroxy-5,3'-dimethoxy-5'-cyclolignan glucoside(1) and micrandiactone H(2),respectively.CONCLUSION:Compunds 1 and 2 are new and neither showed inhibitory effects on nitric oxide(NO) production in lipopolysaccharide-induced RAW264.7 macrophages.
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