Chemical constituents of Euphorbia fischeriana

AIM: To investigate the chemical constituents in the roots of Euphorbia fischeriana. METHODS: The chemical constituents were isolated and purified by various chromatographic techniques. Their structures were identified on the basis of spectroscopic analyses and physiochemical properties. RESULTS: Eleven compounds were isolated and elucidated as (+)-nyasol (1), 23(Z)-cycloart-23-en-3, 25-diol (2), cycloart-22-ene-3, 25-diol (3), ebracteolatain A (4), 2, 4-dihydroxy-6-methoxy-3-formyl-1- acetophenone (5), -linolenic acid (6), 24-methylenecycloartanol (7), cycloartenol (8), -sitosterol (9), 3, 3'-diacetyl-4, 4'-dimethoxy-2, 2', 6, 6'-tetrahydroxy diphenylmethane (10), 2, 4-dihydroxy-6-methoxy-3-methyl-1-acetophenone (11). CONCLUSION: Compound 1 was found in the genus Euphorbia for the first time and compounds 2-6 were firstly isolated from Euphorbia fischeriana.